Cancer bone metastasis is mainly manifested by pain and can be complicated by pathological fracture and bleeding, which seriously affects patients’ quality of life and even causes paralysis. Treatment methods include: 1. radiotherapy: such as local radiotherapy, isotope radiotherapy, local radiotherapy has remarkable efficacy and the clinical efficiency can reach 70%-90%. 1-2 weeks of radiotherapy can significantly relieve pain, and 90% of patients can significantly reduce pain, significantly improve spinal cord symptoms and prevent pathological fracture 3 months after radiotherapy; 2. chemotherapy; 3. biological targeting therapy.