Tooth extraction for toothache is not a clinically recommended treatment, especially for some specific diseases, and it may be relatively contraindicated and even life-threatening if the tooth is extracted during the painful period of the tooth. For example, extraction of wisdom teeth is absolutely prohibited during the acute inflammatory phase of pericoronitis, because the inflammation is relatively heavy at this time, and extraction may cause the spread of infection, resulting in bacteremia or even sepsis, which may be life-threatening in serious cases. Therefore, for toothache, the most important thing is to clarify the cause of toothache, and then make treatment for the symptoms. For example, in the acute stage of pericoronitis of wisdom teeth, anti-inflammatory and analgesic treatment and local irrigation should be given, and then the tooth should be extracted after the non-painful period. Other pains, such as pulpitis, periapical inflammation, trigeminal neuralgia, maxillary sinusitis, all these symptoms can cause toothache. For their treatment, respectively, dental treatment, medication for the symptoms and anti-inflammatory treatment for the inflammation are performed, and extraction is not necessary for the majority of them.