1.When do brain metastases from breast cancer usually occur? Brain metastasis from breast cancer can occur at any time after diagnosis, generally speaking, the median time from the diagnosis of breast cancer to the occurrence of brain metastasis is 2~3 years. 2.What is the prognosis of breast cancer brain metastasis? How long can I live with breast cancer brain metastasis? Generally speaking, the prognosis of breast cancer brain metastasis is related to molecular subtypes, KPS score, number and size of brain metastases, extracranial metastases, etc. Among them, whether or not to receive timely surgical treatment and remove intracranial metastases is the most critical factor to determine the length of patients’ survival. The median survival of patients with symptomatic brain parenchymal metastases is only about 1 month, and about 95%-100% of patients with brain metastases from breast cancer die from progressive increase of intracranial pressure due to tumor and its surrounding edema, so timely diagnosis and surgical treatment in neurosurgery are required.