Grade 1 H. pylori infection does not necessarily require medication. 1. In case of simple H. pylori positivity, not accompanied by symptoms such as gastric discomfort and normal gastroscopy results, the treatment can be done without medication for the time being, but it should be combined with clinical symptoms and regular rechecking of H. pylori with e-gastroscopy. 2. If H. pylori is positive, accompanied by bloating and other dyspepsia, endoscopic manifestations are consistent with H. pylori gastritis, atrophic gastritis, or peptic ulcer, no matter whether the patient has the will of eradication or not, it is recommended to take medication in time for bactericidal treatment, otherwise, gastritis is not easy to recover, and peptic ulcer is prone to bleed, perforation, and even cancer and other complications. If the test results of Helicobacter pylori are abnormal, it is recommended to go to a regular hospital in time, after clarifying the cause of the disease, under the guidance of the doctor for targeted treatment or therapy.