The knee is the largest weight-bearing joint in the body, and osteophytes in this area are very common. No treatment is needed if there are no symptoms, but the main treatment options are medication and surgery, as well as good knee care. Knee osteophytes usually occur in the elderly, but they can also occur in athletes and sports enthusiasts. Therefore, people who enjoy sports must pay attention to the careful protection of the knee joint, and the necessary warm-up activities before exercise and wearing sports braces are effective protective measures. Depending on the severity of the patient’s condition, doctors usually recommend medication for patients with mild symptoms that do not affect walking, and surgery for patients with severe symptoms that affect normal life. Patients can take some analgesic drugs to relieve pain. This treatment can only temporarily improve the patient’s symptoms, and cannot completely solve the problem. There are two main types of surgical treatment. As long as no significant knee damage is caused, the treatment is achieved by surgically removing the severely enlarged bone. If serious knee lesions occur thus affecting function, such as restricted movement, bone defects, and knee deformities, knee replacement is performed so that complete treatment can be achieved. The treatment of osteophytes of the knee joint can be reasonably selected according to the patient’s condition, and attention should be paid to the prevention work.