If a patient has a tingling sensation in the heart due to staying up late, usually for patients with no previous history of coronary heart disease, rest or improved sleep, sublingual nitroglycerin or quick-acting heart pills, or patients taking compound salvia drops, can be relieved and self-help. But for patients with a clear history of unstable angina and arrhythmias in coronary artery disease, a significant tingling in the precordial region after staying up late and the pain gradually worsens, self-help must be carried out in time, otherwise it will lead to acute coronary syndrome. First of all, the patient should try to maintain a calm state of mind, avoid excessive mental tension, anxiety, irritability, etc., and to quickly sublingual nitroglycerin, or quick-acting heart pills and other drugs for self-help. At the same time, if you have anti-platelet aggregation drugs at home, such as aspirin, clopidogrel and other drugs can be taken, and quickly call 120 for help, so that professional doctors with defibrillators and drugs come to the scene to assist in treatment, and quickly arrive at the hospital for the next step of treatment.