Since the main symptoms of myasthenia gravis are muscle weakness and fatigue, there is much controversy regarding the value of exercise therapy in its treatment. There are few studies evaluating exercise therapy and myasthenia gravis, but with reference to the findings of several other neuromuscular diseases, it is clear that exercise can be beneficial in motor neuron disease, motor nerve radiculopathy, peripheral neuropathy and neuromuscular junction transmission disorders, and muscle disease. Becker’s group found that aerobic activity reduced fatigue in patients with myasthenia gravis through low-intensity aerobic activities such as swimming, walking and jogging, and that patients had a higher quality of life and complained of improved fatigue. Rassler’s group evaluated the role of respiratory training in myasthenia gravis, where patients were asked to perform respiratory training five times a week, each time with 30 minutes of intensive normal carbonated breathing, and after 4-6 weeks found an increase in respiratory tolerance, weight loss, and improvement in respiratory muscle weakness symptoms. Limited research suggests that exercise is not a contraindication for myasthenia gravis and that appropriate exercise under professional guidance may help improve quality of life and symptom relief in patients. The following are recommendations and guidelines for exercise in patients with myasthenia gravis: ① Avoid extreme weather activities and running; ② Avoid prolonged endurance exercise, such as running more than 20 km; ③ Figure out the appropriate intensity of exercise for running, hiking and stairs; ④ Exercise after adequate sleep and avoid stress; ⑤ Exercise at the best time of the day.