It is usually not possible to diagnose UTI from the amount of uric acid, and most patients with UTI have uric acid more than 420µmol/L. Uric acid is the end product of purine metabolism, and the saturation concentration of uric acid in the body at 37°C is about 420µmol/L. Above this concentration, urate forms crystals that are deposited in a variety of tissues, including kidneys and synovial membranes of the joints, causing tissue damage. Fasting blood uric acid >420µmol/L on two occasions not on the same day is currently defined as hyperuricemia. Hyperuricemia patients with poorly controlled uric acid will progress to gout, which if left unchecked will involve the kidneys and lead to gouty nephropathy, with the worsening of renal damage will lead to a continuous decline in glomerular filtration rate, and when the glomerular filtration rate is <10 ml/min is usually diagnosed as uremia. Early high uric acid is not necessarily uremia. Most of the patients with uremia have uric acid higher than 420μmol/L. At the same time, there will be primary renal diseases such as chronic pyelonephritis, chronic glomerulonephritis, etc., and secondary renal diseases such as diabetic nephropathy, hypertensive nephropathy and other causes of renal injury, which will cause uremia. To confirm the diagnosis of uremia, it is necessary to complete blood and urine analysis and other related examinations, usually there will be a significant decrease in glomerular filtration rate and endogenous creatinine clearance and proteinuria. If necessary, it is also necessary to improve the renal ultrasound or renal puncture biopsy and other auxiliary diagnosis. There are many causes of uremia, it is recommended to consult a doctor in time and follow the doctor's instructions to standardize the diagnosis and treatment, so as not to delay the condition.