Chronic diseases, mostly from the gradual, if the development of true energy deficiency, sinking disease stagnation stage, treatment is quite difficult, and sometimes even if the medicine and evidence match, the recent effect is difficult to show. The collection of medical treatises by Yue Meizhong says: “The treatment of acute diseases requires boldness, while the treatment of chronic diseases requires prescriptions and guarding”, which illustrates the importance of “guarding prescriptions” in the treatment of chronic diseases. Chronic patients are relatively stable in the remission period, the clinical often because the patient is eager to heal, see can not be quick results, it is necessary to change the prescription; or the doctor is undecided, do not know that the disease is in the stage of subtle quantitative changes, in order to meet the psychology of the patient, change course, another prescription, cold and hot mixed cast, diarrhea and supplementation, and finally attributed to the evidence of the disease is difficult, and lose confidence in the treatment. Therefore, doctors must have a clear understanding and a long-term treatment plan for chronic patients with long-standing deficiency, stagnation, mixed cold and heat, and mixed deficiency and reality. They must clearly explain their reasoning to patients, telling them that the recovery of chronic diseases is a process from quantitative change to qualitative change, and that the key to success lies in keeping the prescription, and encouraging patients to build up their confidence and determination to overcome diseases, so that doctors and patients can cooperate with each other step by step and gradually achieve recovery. For the treatment of chronic diseases, we have learned that the doctor should pay attention to the following points when keeping the prescription: ① To seek the essence in detail, to fully understand the nature of the disease, to achieve accurate identification and legislation. As long as the main etiology of the disease has not changed, the prescription can be kept or changed by adding or subtracting a little on the basis of the original prescription. (3) The medicine should be slow, often with pills and creams. As long as the patient does not feel uncomfortable after taking the medicine, there is no adverse phenomenon objectively, it means that the treatment is appropriate, the adjustment is proper, even if the effect is not obvious, do not arbitrarily change the formula and easy method; otherwise, often because of the ineffectiveness of the formula and miss, the late stage of the disease, often change the soup for the cream pill, slowly figure effect. The study of Chinese medicine treatment rules says: “The treatment of disease not only avoid paranoia, but also requires the doctor to be able to respond in a timely manner. In the specific application, still from two aspects to consider discretion, that is, ‘strain’ and ‘hold the weight’ is to recognize that the basic law of treatment of certain diseases and evidence can not be effective in one or two days, so the treatment must continue this method … … …, so the treatment should master both sides, can hold the weight, there can be strain, biased to either side will be wrong, such as can not hold the weight is the chest is not determined, can not strain is the use of medicine stubborn”. In short, the use of drugs like soldiers, doctors must keep a clear head in the face of the battle, should focus on the overall recovery, so as to avoid the problem of not more not to spare, the more the more wrong, not more also wrong, into the confusion of the formation and no way out.