Getting gonorrhea after the first time you have sex usually requires medication, and commonly used medications include ceftriaxone, cefotaxime, and macrolide. Gonorrhea is a sexually transmitted disease caused by gonococcal infection, and its manifestations include symptoms such as redness, swelling, itching, and mucus discharge from the urethra. For this disease, drug treatment is mostly adopted at present. Its main therapeutic drugs include ceftriaxone, macrolide, cefotaxime and so on. The above medications are suitable for various types of gonorrheal urethritis and gonorrheal uteritis. Gonorrhea patients should follow the doctor’s instructions to apply the full amount of drugs, and should pay attention to personal hygiene in daily life, avoid unclean sexual behavior, and avoid sexual intercourse during the period of illness, so as to avoid infecting others.