The first thing to consider is whether you have eaten cold and irritating food and cold water, or have a cold, which may lead to stimulation of the vagus nerve, causing stomach spasms, resulting in stomach cramps, usually accompanied by nausea, vomiting and other symptoms. In addition, the clinical common acute gastritis and gastroduodenal ulcer caused by gastric colic. 1, acute gastritis: refers to various causes of acute inflammation of the gastric mucosa, common causes are alcohol, drugs, stress, infection, poor dietary habits, mechanical injury, etc.. The main manifestations are epigastric pain, nausea, vomiting and loss of appetite, and the pain can present a burst of colic. In severe cases, symptoms such as vomiting blood, black stool, dehydration and even shock may occur. The diagnosis can be confirmed clinically by gastroscopy. Treatment is based on the principle of targeting the cause, removing the damaging factors, and actively treating the primary disease; 2. Gastroduodenal ulcer: generally due to excessive secretion of gastric acid, Helicobacter pylori infection or weakened mucosal defense mechanism. When there is acute perforation, patients will have sudden and severe pain in the upper abdomen, which can be manifested as colic, often accompanied by nausea and vomiting, and patients will have pale face and cold sweat, which require emergency treatment. When a scarring pyloric obstruction is formed by gastroduodenal ulcer, patients will also show abdominal pain and repeated vomiting. Abdominal pain is mainly manifested as paroxysmal epigastric pain, which is a burst of colic in the stomach; 3. Heart attack: When a heart attack occurs, there will be persistent crushing pain in the precordial region, which some patients may mistake for stomach colic. Heart attack is usually caused by coronary atherosclerosis, and the age of onset tends to be younger and younger. In addition to the influence of disease factors, strenuous exercise, mood swings and overexertion are also likely to trigger heart attack. In addition to pain, patients usually have symptoms such as weakness, palpitations, chest tightness and shortness of breath, etc. Sublingual nitroglycerin can generally relieve the symptoms. Patients with underlying cardiovascular disease or with the persistence of the above symptoms are advised to call 120 or seek immediate medical attention. In addition, it should be noted that diseases such as acute cholecystitis and acute pancreatitis can also manifest as epigastric pain, which may be perceived as pain and colic in the stomach. If you feel that stomach colic persists it is recommended to seek medical attention to clarify the diagnosis so as not to delay treatment.