Finger (toe) bone infarction is one of the symptoms of sickle cell anemia (crescentcellanaemia, sickle-cellanemia), which is a hereditary blood disorder and can also become a pure-hybrid sickle cell disease, and its clinical manifestations are: there are varying degrees of hemolytic anemia and mild jaundice. Vascular occlusive crisis is its prominent manifestation, often with severe pain at the trunk and extremities, including visceral, bone, joint and muscle pain, especially metacarpal, epiphyseal and finger (toe) bone infarcts are common, with infection, dehydration, hypoxia and acidosis as its causative factors. Infection, dehydration, hypoxia and acidosis are the causes. Visceral and cerebrovascular infarcts present with corresponding signs and symptoms. If both spouses are carriers of the sickle cell anemia gene, their children are 25% more likely to have severe sickle cell anemia and 50% more likely to have mild sickle cell anemia. Currently, 50 million people worldwide are at risk for sickle cell anemia. In Africa alone, 300,000 newborns are carriers of the sickle cell anemia gene each year, and 50% of them die before the age of 5. The following diseases are also causes of finger (toe) bone infarction: 1. Congenital dyserythropoietic anemia Congenital dyserythropoietic anemia (CDA) is a rare inherited familial disorder of ineffective hematopoiesis of the red blood cell lineage. It is characterized by chronic, refractory mild or severe anemia with persistent or intermittent jaundice and bone marrow manifestations of ineffective erythropoiesis, multinucleation, nuclear fragmentation and other morphological abnormalities. 2.Sickle cell nephropathy The kidney damage caused by sickle cell disease is called sickle cell nephropathy. Sickle cell nephropathy is a hemoglobinopathy caused by abnormal hemoglobin, with hemolytic anemia as the most common, accompanied by low specific gravity polyuria, suggesting that the patient has abnormal renal tubular function.