High HCG may be caused by pregnancy, ectopic pregnancy or trophoblastic disease, and needs to be diagnosed after examination. 1. pregnancy: if a woman’s HCG is >5.0U/L, it generally indicates pregnancy, and in the early stage of pregnancy, HCG can show a doubling in 48 hours, in addition, the HCG of pregnant women with twin or multiple pregnancies is usually higher than that of pregnant women with singleton; 2. ectopic pregnancy: if a woman has a high HCG during pregnancy, it may also be ectopic pregnancy, and if it is confirmed to be ectopic pregnancy, ultrasound examination is needed after blood and urine examination; 3. trophoblastic disease: for example, staphyloma, choriocarcinoma, etc. If the HCG is high, it may also be ectopic pregnancy, after blood and urine examination, ultrasound examination is needed, if it is confirmed to be ectopic pregnancy, the pregnancy should be terminated in time; 3, trophoblastic diseases: for example, staphyloma, choriocarcinoma, etc., the serum HCG concentration in early pregnancy can reach 200000 IU/mL, at this time, it is highly suspected to be staphyloma, if it is confirmed, it should be given clearance surgery as soon as possible.