Acne is a common condition that occurs on the face and is extremely prevalent. The disease is not restricted to any one age group and can develop in almost all age groups, from children to adults. As the standard of living has improved in recent years, the effective treatment of acne has received increasing attention and focus. Without proper treatment, acne can turn into grade 3, 4, with nodules, cysts or scarring in addition to acne, inflammatory papules and pustules. ALA, as a photosensitizer, has a wide range of applications and can be used for acne, actinic keratosis, various skin diseases, bladder cancer, acromegaly, upper gastrointestinal tract cancer, rectal cancer, breast cancer, bright red nevus, age-related macular degeneration, rheumatoid arthritis and other diseases . For example, the cure rate for acne is over 95%, and satisfactory results have been achieved.