TSH8.49μIU/ml, higher than the normal range, but not absolutely need to take drugs, if the diagnosis of clinical hypothyroidism or subclinical hypothyroidism accompanied by dyslipidemia, you can follow the doctor’s instructions oral levothyroxine tablets treatment. 1. Patients with clinical hypothyroidism need to take medication. TSH is the abbreviation for serum thyroid stimulating hormone. If TSH is elevated, accompanied by a decrease in free T3 and free T4, and the patient experiences symptoms of hypothyroidism such as fatigue, loss of appetite, hair loss, and depressed mood, clinical hypothyroidism is diagnosed. This condition usually requires medication and can be treated with levothyroxine tablets to supplement thyroxine as prescribed by the doctor. 2. In subclinical hypothyroidism, the decision to take medication needs to be made in conjunction with blood lipid levels. If TSH is elevated but free T3 and free T4 are normal, subclinical hypothyroidism can be diagnosed. Patients with subclinical hypothyroidism, if accompanied by abnormal lipid levels, can take oral levothyroxine tablets as an alternative treatment. To summarize, whether TSH8.49μIU/ml needs to be treated with medication needs to be determined in combination with free T3, free T4, lipid levels, etc. The use of medication needs to comply with the doctor’s instructions, and should not be abused on its own.