Hand blistering and itching may be caused by mosquito bites, may also be blistering ringworm or sweat herpes, etc., usually consider the external application of medication ointment or oral medication. 1. mosquito bites: mosquito bites, mosquito toxins will cause local skin allergic reaction, resulting in blistering itchy hands, can be applied externally compound camphor cream to stop itching, and in severe cases under the guidance of a doctor to take loratadine tablets, such as anti-allergy treatment. 2. Blistering tinea versicolor: If the fungal infection causes blistering and itching of the hands, consider blistering tinea versicolor, you can externally apply antifungal medication ointment, commonly used medications such as ketoconazole cream, lilac naphthalene ester cream, and so on. 3. Sweat herpes: If regular sweating causes hand blistering and itching, consider sweat herpes, belonging to a kind of skin inflammation, generally in the hands after washing, topical application of salicylic acid ointment, mometasone furoate cream, tacrolimus ointment. Hand blisters and itching may have other reasons, it is recommended to go to the regular hospital, after a clear diagnosis, according to the doctor’s prescription medication, do not take care of yourself.