Fetal bilateral choroid plexus cysts generally do not have much effect on the fetus, more than 90% of them can subside naturally, and after subsiding, they have no pathological significance and basically have no effect on the subsequent growth and development of the fetus. Only a few of them show progressive enlargement, and the cause needs to be clarified for treatment and management. If the bilateral choroid plexus cysts disappear on their own at around 26 weeks of pregnancy, there is usually no compression or increase in cranial pressure, and postnatal intelligence or other aspects of life will not be affected by the choroid plexus cysts. If the choroid plexus cysts do not disappear after 26 weeks and are bilateral, 4D ultrasound or amniocentesis can be done to check the development of the fetus. If the fetus is not associated with other developmental abnormalities, the pregnancy can be continued; if there are serious developmental abnormalities, which will affect the quality of the fetus’ postnatal survival, termination of the pregnancy should be considered. If the choroid plexus cyst still exists after birth, it may compress the cerebral nerves and cause developmental backwardness. Cranial examination and chromosomal examination of umbilical cord blood cells are needed to actively carry out treatment and improve the prognosis. Bilateral fetal choroid plexus cysts alone often have no clear pathologic significance and have a good prognosis, but the condition is associated with an increased risk of chromosomal abnormalities (trisomy 18-trisomy, trisomy 21-trisomy), and prompt prenatal diagnosis and testing of fetal chromosomes is recommended.