Anti-Helicobacter pylori infection bismuth potassium citrate is taken before breakfast and dinner, and the quadruple regimen containing bismuth (PPI + bismuth + 2 antibiotics) recommended by China’s Fifth National Consensus Report on the Management of Helicobacter pylori Infections, in which bismuth potassium citrate is dosed at 220mg. Bismuth potassium citrate is taken half an hour before breakfast and dinner to avoid taking it together with antibiotics, which can affect the efficacy, and is taken twice a day. Helicobacter pylori infection is mainly treated with quadruple or triple therapy. Triple therapy is two antibiotics plus a bismuth agent; quadruple therapy is usually two antibiotics, such as clarithromycin, amoxicillin, etc., plus a proton pump inhibitor, such as omeprazole, esomeprazole, etc., combined with bismuth potassium citrate. It is recommended to standardize the use of medication according to the guidance of the physician, and not to take it blindly on your own.