A sore throat accompanied by yellow sputum is mostly suggestive of a bacterial infection, which may be a viral infection secondary to a bacterial infection or an upper respiratory tract infection due to a separate bacterial infection. Anti-viral drugs combined with antibiotics can be chosen. Anti-viral drugs such as oseltamivir, ribavirin or Chinese patent medicine anti-viral oral solution, and antibiotics such as penicillin, amoxicillin, cefuroxime, cefaclor, clindamycin, azithromycin, roxithromycin, and levofloxacin. You can also supplement with phlegmolytic drugs, such as eucalyptus pinene and carboxymethylstilbestrol, and enhance back patting to promote phlegm expulsion. If other symptoms such as fever and chest pain occur, it is recommended to go to the hospital for further examination or treatment with intravenous medications.