It is usually not recommended to take medication with lemonade because lemonade is a drink rich in vitamin C, but it is also an acidic drink. Acidic beverages have a certain degree of drug resistance and decomposition of drugs, for antibiotics are usually anti-inflammatory drugs, such as cephalosporin, azithromycin, ofloxacin, these drugs in lemon water when taken, it will make the pharmacokinetics and pharmacokinetics of the obvious discount, and lead to secondary failure of antibiotics. If the lemon water is taken with gastric drugs, such as proton pump inhibitors, gastric mucosal protective agents or compound bismuth drugs, such as taking omeprazole, Nexium, mazurin and other drugs, citric acid will destroy the mucosal barrier of the gastric mucosa at this time, and lead to secondary failure of such drugs. Lemon water can be sent to take antiviral drugs, such as ganciclovir and acyclovir, etc., but it will make the stomach acid secretion, leading to abdominal discomfort symptoms aggravated, in short, with lemon water to take medication is not recommended.