Itchy body in bed if caused by environmental factors should be timely cleaning sheets, etc., if caused by urticaria can take antihistamines to relieve. 1. Environmental factors: itchy symptoms when sleeping in bed, can be caused by the bedding is not clean, you should change the sheets, more sunshine quilt, to reduce the breeding of mites, bacteria. It can also be caused by dry skin, you can use moisturizer to relieve itching. 2. Urticaria: If urticaria exists, due to the vagus nerve excitation at night, it is more likely to appear itchy phenomenon, and at the same time, there will be symptoms such as air masses. Oral antihistamines such as loratadine and cetirizine can be taken to relieve the symptoms. If the phenomenon of itching all over the bed is obvious, you should go to the hospital in time for examination, standardized treatment under the guidance of the doctor, the use of the above drugs need to follow the doctor’s instructions.