Parkinson’s disease (PD) is a progressive neurological disorder that primarily affects the motor function of patients. Parkinson’s disease is caused by neuropathy in a part of the brain called the substantia nigra. Various parts of the brain coordinate all of our thoughts, movements, emotions and sensations by sending signals to each other. For example, when we want to move our limbs, the brain sends signals to the relevant nerves, which are then transmitted and integrated one level at a time, causing the relevant muscles to contract and relax and the limbs to move. One part of this complex process is that the basal ganglia sends a signal to the thalamus, which then transmits the signal to the cerebral cortex and other parts of the brain. The signals from the nerve cells in the brain are transmitted through certain chemicals called “neurotransmitters”. A chemical called dopamine (neurotransmitter) is produced by the nigrostriatal cells of the brain, which are also necessary for the transmission of normal motor signals. When nigrostriatal cells die, they can no longer produce and send dopamine, so that normal motor signals cannot be transmitted. Another chemical in the brain called acetylcholine (also a neurotransmitter) is also controlled by dopamine. When there is an insufficient amount of dopamine, there is an excessive amount of acetylcholine. These problems result in the patient’s inability to control the movement of the limbs properly, i.e., muscle tremor/strengthening. In 1817, James Parkinson, an English physician, was diagnosed with the disease. James Parkinson, an English physician, was the first to systematically describe the clinical picture of the disease. Because the main manifestations of the disease are tremor and tonicity, it was first called “shaking palsy”, and this name is still used in our old textbooks. Later, the disease was observed more carefully, and it was found that in addition to tremor and muscle rigidity, patients also had other symptoms as manifestations, and the actual strength of the muscles of the limbs was not impaired, so it was thought that simply calling it “tremor” and “paralysis” was not appropriate. “Therefore, it is suggested that the disease be named “Parkinson’s disease” and commemorate the early medical doctor.