Minimally invasive removal of gallstones Based on the laparoscopic treatment of gallbladder stones in close cooperation with the endoscopy room. We have successfully combined choledochoscopy and duodenoscopy for minimally invasive treatment of gallbladder stones and common bile duct stones, plus last year we carried out biliary preservation surgery. With the organic combination of the three scopes, the specific analysis of each case, it has become a very effective minimally invasive biliary surgery center for the treatment of various biliary tract disorders. The prevalence of gallstone disease in China is 0.9% – 10.1%, with a trend of increasing year by year. Traditional surgery is effective, but has high complication and residual stone rate. Minimally invasive surgery is less invasive, less painful for patients, faster recovery, and can effectively reduce or avoid the medical trauma and complications caused by traditional surgery. In recent years, with the widespread use of cholangioscopic technology. Duodenoscopy and laparoscopy techniques have been popularized by rapid development. The organic combination of the three mirrors has become a very effective minimally invasive biliary surgery for the diagnosis and treatment of gallstone patients. Under the guidance of Director Shi Zengxiang, the medical and nursing staffs of the general surgery ward have focused on the subspecialty of general surgery. In the subspecialty of general surgery, they focus on minimally invasive liver, biliary and breast surgery. Last year, they successfully carried out biliary and breast surgery. This year, they focus on the minimally invasive treatment of common gallbladder stones and common bile duct stones. With the introduction of duodenoscopy in our hospital. The conditions for minimally invasive treatment of common bile duct stones are available. Minimally invasive treatment of common bile duct stones, gallbladder stones, mainly has the following 3 methods: 1, laparoscopic cholecystectomy, with choledochoscopic exploration of the common bile duct (LCBFD+LC) 2, first duodenoscopic papillary sphincterotomy followed by laparoscopic cholecystectomy (EST+LC) 3, duodenoscopic expansion of the papillary sphincter capsule in elderly patients and critically ill patients. EST+LC with LCBDE+LC has short operation time, low complication rate and low treatment cost. It is also a minimally invasive procedure with little pain. Postoperative recovery is fast. Especially the patient is in good condition. One-stage common bile duct suturing can be performed. The advantages of minimally invasive can be better reflected.