Due to anatomical, physiological and poor hygiene habits, girls are susceptible to vaginitis. When treating vaginitis in girls, attention should be paid to the following aspects: first, keep the vulva clean and dry, reduce friction; second, choose the appropriate oral antibiotic treatment for the pathogenic bacteria, or use a pipette to enter the vagina with antibiotic solution; third, symptomatic treatment, and if there are worms to give deworming treatment. If there is a foreign body in the vagina, the foreign body should be taken out in time. Adhesions to the labia minora can mostly be loosened with topical estrogen cream. In severe cases, the adhesions should be separated and antibiotic ointment should be applied.