Clinically, idiopathic swelling is generally defined as swelling for which no cause can be found. Non-idiopathic swelling, for which a cause can be found, can be seen in mucinous swelling due to hypothyroidism, in chronic nephritis or nephrotic syndrome due to massive proteinuria, and in peripheral venous stasis due to cardiac insufficiency and heart failure. In addition, plasma hypoalbuminemia due to decreased protein synthesis by the liver and the subsequent decrease in plasma osmolality is also a cause of edema. In addition, the use of antihypertensive drugs such as calcium channel blockers or hypoglycemic drugs such as pioglitazone can also cause swelling. All swelling other than these causes is called idiopathic swelling and can be left untreated if the patient has no specific discomfort. If the patient has discomfort, a combination of drugs such as furosemide or spironolactone can be applied symptomatically to reduce and improve the symptoms.