Women can have sex after amenorrhea. However, after amenorrhea, due to the decline in ovarian function, estrogen and progesterone levels are very low, so the patient may experience pain or difficulty in sexual intercourse. Because of the decrease in hormone levels, the reproductive tract may gradually atrophy and the folds of the vagina may decrease. Therefore, the elasticity of the vagina during intercourse is not good and friction pain may occur. The secretory glands of the vaginal genital tract will also secrete less, and the number will be reduced. So the patient will have less vaginal secretions during intercourse and will also experience pain and discomfort. If the patient’s vagina is particularly atrophied, there may be difficulty with intercourse. In this case, patients can choose to use local estrogen topical application, or add systemic use of estrogen drugs to carry out treatment.