Numbness and swelling of the hands when sleeping, if not relieved quickly, accompanied by mild immobility of the hands, or salivation at the corners of the mouth, should be considered to be caused by acute cerebrovascular disease. For example, mild cerebral hemorrhage or cerebral infarction or transient ischemic attack may cause numbness and swelling in the hands. Generally, the lesion is located in the thalamus or in the cerebral bridge, so it is important to see a hospital for examination and treatment in a timely manner. There is also a numbness and swelling of the hand when the patient gets up from sleep, if the activity can be reduced, it should be considered to be caused by cervical spondylosis, which may be caused by the patient’s improper posture during sleep at night, resulting in the protrusion of the cervical disc and compression of the nerve root, and the patient will have the symptoms of numbness and swelling of the hand. And if the patient is always numb and swollen hands in the morning, consider that the patient may have rheumatism system diseases caused by the patient, it is recommended that the patient visit the hospital for rheumatism series of examination.