Diabetic foot ulcer is one of the many chronic complications of diabetes and a major factor affecting the survival and quality of life of diabetic patients. This disease is mostly caused by poor glycemic control due to factors such as failure to systematically control diet, failure to take glucose-lowering medications on time or failure to regularly monitor the effects of treatment, resulting in peripheral nerve damage and peripheral vascular lesions in patients. This injury and lesion eventually lead to this chronic refractory ulcer under certain causative factors. This disease, if not treated properly or in a timely manner will result in inevitable amputation, causing great pain to the majority of patients. The main manifestations of diabetic foot lesions are: numbness, coldness, pain, pale or purple color of the foot in the early stage; exudation after the occurrence of rupture, long time without healing or repeated rupture; in severe cases, the toes and even the lower leg become black and necrotic, pus exudation, bad odor, severe pain and sleepless nights, accompanied by fever and other systemic symptoms. The treatment of this disease has the following aspects: on the basis of blood sugar control, Chinese herbal medicine can be applied to activate blood circulation and eliminate blood stasis, clear heat and dampness, and benefit qi and nourish yin to improve symptoms and promote wound healing. In addition, for patients characterized by ischemic pain, appropriate surgical methods can be selected for treatment, such as vascular bypass surgery, minimally invasive catheter treatment and the latest stem cell transplantation. Prevention of diabetic foot ulcers: 1. Strictly follow the doctor’s instructions to control diet, control blood sugar and monitor the effect of treatment. 2, diabetic patients should pay attention to the protection of their feet. Wear shoes of the right size; be careful when trimming toenails; avoid burns when washing the feet; keep the feet clean; 3. If symptoms such as numbness and pain in the limbs are found, they should be seen by a specialist hospital in a timely manner.