Diseases of the tongue, inflammation and injury of the organs adjacent to the root of the tongue can cause pain at the root of the tongue. 1. Tongue diseases: attacks of glossopharyngeal neuralgia can cause sudden and severe pain at the base of the tongue. Lobular papillitis of tongue can cause slight pain in the root of tongue. Early stage of tongue cancer is usually asymptomatic, occasionally there may be slight irritating pain, and in the late stage, it may extend backward to the root of the tongue and cause severe pain. 2. Inflammation of neighboring organs at the root of tongue: tonsillitis, pharyngitis, etc., which can cause pain at the root of tongue. 3. Injury: Eating too hot food can cause burns on the mucous membrane of the root of the tongue, causing pain at the root of the tongue. There are many causes of pain at the base of the tongue, it is recommended to go to the hospital in time and timely treatment.