Numbness and weakness of both hands may be related to physiological factors such as excessive fatigue, or may be caused by peripheral neuritis, cervical spondylosis and other reasons. 1. Physiological factors: If you are engaged in the labor of lifting heavy objects for a long time, resulting in the hands being in a state of excessive fatigue for a long time, it may cause numbness and weakness of both hands. It can be relieved quickly with proper rest and no special treatment is needed. 2. Peripheral neuritis: due to aseptic inflammation of the nerve terminal, under the stimulation of inflammatory factors, resulting in damage to the peripheral nerves, which may cause sensory impairment of the distal limbs, resulting in numbness and weakness of the hands, which may also be accompanied by inflexible hand movement, swelling and other symptoms. 3. Cervical spondylosis: usually caused by long-term improper posture, which can lead to changes in the normal physiological curvature of the cervical spine, which can easily lead to local nerve root compression, and may cause numbness and weakness of both hands, and may be accompanied by dizziness, neck and shoulder pain and other symptoms. The numbness and weakness of both hands may be caused by other reasons. If the symptoms are serious, the patient should consult a doctor as soon as possible to confirm the diagnosis of the causative factors and then give targeted treatment.