If the wound is not infected and is small, it can mostly heal. However, if the diameter of the wound is more than 3 centimeters, it will not heal completely. Meanwhile, wounds that are difficult to heal need to be treated according to the cause in order to promote their healing. If the wound is not healing due to uneven growth of granulation tissue, the cavity can be excised and sutured at the same time to promote the re-growth of granulation tissue, thus promoting healing; or the wound can be surgically covered with a flap or grafted piece of skin and treated with medication changes to heal the wound. If the wound is small, local massage, physiotherapy, infrared irradiation and other physical therapy methods, while topical growth factors, improve local blood circulation, etc., to make the newborn granulation tissue proliferation in the hole, to promote wound healing. In the process of wound healing, you also need to pay attention to the prevention and treatment of infection, can be regular disinfection of the wound, dressing change, or take amoxicillin, cefaclor and other antibiotics.