Spots on the face at the age of 44 commonly include chloasma, freckles and age spots. They can be treated by drugs and physical methods. 1. Melasma: it refers to yellow-brown pigmentation spots on the face, which may be related to genetic susceptibility, ultraviolet irradiation, change of sex hormone level, etc. The lesions may be light yellow-brown, dark brown or dark coffee-colored spots with variable depth. The skin lesions may be light yellowish brown, dark brown or dark coffee-colored spots with variable depth. You can use hydroquinone cream and vitamin A acid cream alternately or mixed externally as prescribed by doctor, and take vitamin C orally to lighten melasma. 2. Freckle: It refers to hyperpigmentation spots occurring on the facial skin, mainly light brown to dark brown spots. The skin lesions are yellowish, yellowish-brown spots, which are round, ovoid or irregular in shape, ranging from the head of a needle to the size of a grain of rice or larger. They can go to specialized hospitals for photoelectric treatment, such as pulse light, Q laser, ruby laser, etc., and generally have better treatment effect. 3. Age spots: it is a kind of skin degeneration of the elderly, and its occurrence is related to natural aging, sunlight damage, genetic factors and so on. Generally, the lesions are 1 or several yellowish or light brown flat papules or plaques that are slightly higher than the skin surface. If it does not affect the life, generally do not need treatment, can use high-frequency electric knife, C6 and other photoelectric treatment to improve. In addition, 40-year-old patients with spots on the face and the willingness to improve it are recommended to go to a regular hospital and follow the doctor’s instructions for treatment.