What are the adverse effects after cholecystectomy? There are probably the following: 1. indigestion and reflux gastritis; 2. the problem of bile duct injury after cholecystectomy; . Bile duct injury after cholecystectomy accounts for about 2%; 3, the increased incidence of common bile duct stones after cholecystectomy statistics, the incidence of common bile duct stones is 2:1 for patients with and without gallbladder removal; 4, the effect of cholecystectomy on the incidence of colon cancer; relevant European medical literature statistics, the incidence of colon cancer will greatly increase after cholecystectomy; 5, post-cholecystectomy syndrome. including upper abdominal fullness and discomfort after eating fatty food, indigestion, steatorrhea, etc.