Half of the face is swollen with acne, which may be secondary infection of acne, and the main treatment methods are general treatment, topical medication and oral medication. 1. General treatment: Acne secondary infections need to pay attention to keep the local dry and clean, and at the same time, avoid face water, pay attention to rest, avoid staying up late, avoid eating sweet, spicy and stimulating food. 2. Topical medication: Patients with secondary acne infections can also use topical fusidic acid cream, mupirocin ointment, erythromycin ointment and other medications under the guidance of a doctor for anti-infective treatment. 3. Oral drug treatment: If the infection is serious, the effect of local drugs is not good, patients also need to follow the doctor’s instructions to use oral amoxicillin capsules, cefuroxime tablets, cefixime capsules and other anti-infective drug treatment. If the above situation occurs, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor’s treatment.