Stem cell facial filler is usually a facial filler performed by stem cells in combination with fat tissue. Because the fat alone is derived from stem cells, its extraction and volume are small and cannot complete the role of filler, but only play the role of skin cell regeneration. The biggest danger of this operation is that fat injected into the face can easily reach the blood vessels and block the veins, which can easily cause poor return flow and lead to vascular embolism. If the operator does not strictly follow the operation protocol to pump back before injection during the fat injection process, the fat may be injected into the blood vessels, blocking the vascular cavity of small vessels, and the local skin of its blood supply area will be blackened and the patient will feel pain; if the large blood vessels are blocked, such as the blockage of the eye artery, it can lead to the patient’s immediate blindness. In addition, stem cell fat is fat that has been treated with high quality, and the fat survival rate is about 90%, about 10% of the fat cannot be viable, and part of the fat that cannot be viable will be discharged out of the body with metabolism, and the remaining may be liquefied, resulting in the patient’s skin depression, and there may be fluid, accompanied by pain, local redness and swelling, etc. It is recommended that candidates can go to a regular medical beauty institution and choose an experienced surgeon to perform the operation to reduce the risk of surgery.