When myocardial ischemia can not sleep, under the guidance of the physician for the treatment of the primary disease and sleep aid treatment. 1. Treatment of primary disease: through the treatment of primary disease, the symptoms can be relieved to improve sleep, under the guidance of the physician to apply nitroglycerin, aspirin, metoprolol, nifedipine, captopril, simvastatin and other drugs for treatment, but also according to the patient’s condition, angioplasty, stenting and other interventional treatments, as well as coronary artery bypass grafting surgery and other surgical treatments. 2. Sleeping aid treatment: When patients suffer from long-term insomnia, their condition may be aggravated due to the inability to get a good rest, so they can be treated with sleeping aids such as alprazolam, dexzopirox and eszopiclone under the guidance of physicians. When symptoms of myocardial ischemia occur, they should be diagnosed and treated in a timely manner and medication should be administered as prescribed by the doctor.