Male nipple protrusion can have both physiological and pathological causes. It is recommended to consult a doctor to identify the cause of the disease and standardize the treatment. 1. Physiological reasons: male nipple protrusion, because in puberty the body androgen and estrogen balance, the body’s hormone exuberance, male breasts began to develop, the development of men, will cause male nipple protruding, by the outside world’s stimulus, such as cold, etc. will lead to nipple protrusion. 2. Pathological reasons: it is possible that the male nipple estrogen secretion is too high, after the estrogen is high, there will be a secondary development, excessive obesity can also cause male nipple protrusion, a large amount of fat pushed in the breast will result in the mammary gland volume becomes larger, this disease is called gynecomastia. Male breast tumors can also cause nipple protrusion, such as male breast cancer, etc., which need to be diagnosed as soon as possible and treated surgically. There are many uncertain factors that can cause male nipple protrusion, if the nipple protrudes and is accompanied by some other uncomfortable symptoms, it is recommended to go to the relevant departments of the regular hospital for further examination, and the specific results of the examination for drug treatment.