After general anesthesia, the anesthetic may stimulate the brain and cause memory loss, mainly short-term memory loss will be more obvious, there are also individual will appear a long period of memory loss. Generally, memory loss after general anesthesia occurs mainly in middle-aged and elderly patients, most of whom will have some underlying diseases. Some patients will have vascular disease, after the anesthetic will accelerate the patient’s memory loss. In clinical practice, it is necessary to be alert to elderly patients over 80 years of age, whose number of general anesthesia should be minimized. This is because elderly patients over 80 years of age are likely to experience severe memory loss after general anesthesia, and this severe decline is less effective with medication. Generally, after about six months of memory loss after general anesthesia, most of them can return to the normal state.