It is also known as age-related macular degeneration. It is the leading cause of blindness in developed countries, with a prevalence of more than 40% over the age of 75. AMD is increasing in China. Risk factors. 1. Age. The prevalence of AMD was 4.2% at the age of 43-54 years and 46.2% at the age of 75 years and above. The older the age, the higher the risk factors. 2, Genetic. Related to genes. 3, smoking. Increases the risk of MAD by a factor of 2 and is dose-related. 4.High blood pressure. 5, High blood lipids. 6, Sun exposure. Aging causes low antioxidant levels in the body. Clinically, there are two types: atrophic type. Slow onset with reduced visual acuity. Vitreous warts and pigment disorders are seen in the posterior pole of the fundus. Exudative type. Sudden monocular vision loss, distorted vision or central dark spot. Retinal hemorrhages and exudates are seen in the posterior pole of the fundus, in which grayish-yellow lesions are sometimes visible. Scar mechanization develops over time. Progressive loss of vision in both eyes in patients over 45 years of age should be taken seriously. Do fluoroscopy. Treat the exudative type. Macula 500 μm out, fundus laser closure. Anti-VEGF drug treatment.