Knee and ankle pain, such as acute injury should be taken for braking, cold compresses, hot compresses and active participation in the recovery treatment, such as arthritis should be taken for anti-inflammatory, analgesic and corresponding to different categories of arthritis targeted treatment. 1. caused by acute injury: in the beginning of the pain, to immediately reduce the knee ankle strenuous exercise, to prevent the injury part of the injury again aggravated. 72 hours to take the cold compress method, reduce the local inflammatory response 72 hours after the use of hot water bags hot compresses, to promote blood circulation, speed up the speed of recovery. To go to the hospital in time to clarify the injury, and actively cooperate with the diagnosis and treatment plan formulated by the doctor. Actively participate in the recovery treatment of the knee ankle joint, through a variety of sports to strengthen the consolidation of the knee ankle joint strength, reduce the occurrence of secondary injuries. 2. caused by arthritis: according to the different types of arthritis to take targeted treatment. Rheumatoid arthritis can be achieved through joint braking, or the use of non-steroidal anti-inflammatory drugs, glucocorticoids and so on. Osteoarthritis using non-steroidal anti-inflammatory drugs, glucosamine, bisacodyl ryanin and so on. Septic arthritis should identify the causative organism and use targeted sensitive antimicrobials such as ceftazidime. Knee, ankle pain should be timely consultation, clear cause, do not take medication, so as to avoid unnecessary harm.