Clobetasol propionate ointment can be used for the treatment of psoriasis of the common type, the course of treatment should depend on the condition of the doctor’s advice, usually not more than 4 weeks. Clobetasol propionate ointment is a compound preparation composed of clobetasol propionate and retinoic acid, which can inhibit the proliferation of keratinocytes and inhibit the chemotaxis of leukocytes, and has anti-inflammatory and antikeratinization effects, and is clinically used for the treatment of psoriasis of common type. Clobetasol propionate ointment should be used by dermatologists depending on the condition of the disease, the general course of monotherapy does not exceed 2 weeks, based on efficacy and safety considerations up to 4 weeks. Clobetasol propionate ointment is contraindicated in cases of hypersensitivity to the components of this drug and in pregnant women in the first trimester of pregnancy. Adverse reactions such as local irritation, itching, stinging, cracking and drying of the skin, hirsutism, acne-like rashes and even hyperglycemia may occur after use. It should be used under medical supervision and in case of discomfort, seek medical attention.