Darkened labia of middle-aged women may be caused by endocrine disorders, vulvodynia and vulvar melanoma. 1. Endocrine disorders: as middle-aged women grow older, hormonal imbalance in the body may lead to darkening of the labia. 2. Vulvovaginitis: if middle-aged women suffer from vulvovaginitis, because the labia area is stimulated by inflammation, it is easy to appear the phenomenon of darkening of the labia, accompanied by vulvar itching, increase in vaginal secretion and other symptoms. 3. Vulvar melanoma: after middle-aged women suffer from vulvar tumor disease, it may be due to malignant tumor occupying lesion, thus appearing the manifestation of black labia, accompanied by black papules or black spots, and the surface of the surface will be erosion, or even ulcers and other symptoms. Middle-aged women with black labia and other physical discomfort, it is recommended that the patient go to the hospital in a timely manner. Improve the relevant examination, under the guidance of specialists to actively deal with. In ordinary life to keep the vulva clean, and change underwear.