Diabetes mellitus increases the risk of osteoporosis due to insulin deficiency, calcium loss, and inadequate calcium intake that can disrupt the balance of bone metabolism. Diabetics are at increased risk of osteoporosis. Firstly, diabetes mellitus, due to decreased pancreatic function and insufficient insulin in the body, there will be impaired protein synthesis and reduced bone matrix formation; secondly, diabetic patients with high blood glucose concentration, the kidneys excrete too much glucose at the same time, the filtration rate of calcium ions increases, resulting in a large amount of calcium loss from the urine, which will lead to osteoporosis. In addition, diabetic people due to diet control, daily calcium intake is insufficient, will also accelerate the occurrence of osteoporosis. Therefore, diabetic people should be alert to the occurrence of osteoporosis, develop a good lifestyle, and if necessary, under the guidance of the doctor reasonable treatment.