The pharmacological effects of Isotretinoin Capsules for the treatment of acne are the inhibition of the growth of Propionibacterium acnes number, modulation of inflammatory immune mediators and selective binding of retinoic acid nuclear receptors to exert therapeutic effects. Isotretinoin can reduce sebaceous gland tissue, inhibit sebaceous gland activity, reduce epithelial cell keratinization and keratin embolism of follicular sebaceous gland orifices, and inhibit the growth and reproduction of Propionibacterium acnes. It also exerts therapeutic effects by modulating inflammatory immune mediators as well as selectively binding to retinoic acid nuclear receptors. The mode of action of topical isotretinoin may induce epidermal cell proliferation, promote differentiation of cells from the granular layer of the epidermis to the stratum corneum, and remove keratin plugs by regulating the abnormal process of epithelial keratinization of the sebaceous glands of the hair follicles, which may play a role in the prevention and elimination of acne lesions. Isotretinoin can be used in the treatment of topical common acne and pimples, the use of this product can be dry skin, lipitis, desquamation, itching, pain, rash, conjunctivitis, depression, benign cerebral hypertension, osteoporosis, muscle weakness, pain, elevated liver enzymes, increased lipids, platelet drop, and other adverse reactions, and most of them can be relieved after discontinuation of the drug. Skin epithelial cell tumor personal history or family history of patients, broken, eczema-like or sun-burned areas of the skin pregnant and lactating women, hepatic and renal insufficiency, allergic to the product is prohibited. Patients who want to use isotretinoin to treat acne are advised to go to a regular hospital, consult a professional doctor, and cooperate with the doctor to complete the relevant examinations to clarify the cause and avoid blind treatment.