Cranial repair is a surgical procedure for patients with cranial defects caused by cranial trauma and diseases. The role of the surgery is mainly to repair the defective part of the skull and rebuild the protective shell of the soft tissue of the brain. At present, with the rapid development of economy, more and more people are suffering from cranial defects due to traffic accidents, falling objects, various intracranial diseases, etc., which makes cranial repair a common surgery. Currently, most hospitals are using titanium mesh material for cranial repair, which has certain disadvantages, such as poor compatibility, high infection, and thermal conductivity, relative imperviousness to X-ray and foreign body reaction. We use the new PEEK material to do cranial repair, PEEK material cranial repair surgery after light weight, no foreign body feeling, no stress collapse concerns elastic modulus close to the autologous bone, reduce the “stress shielding”. In addition, CT/MRI tracking is easy, and there is no artifact interference with brain pacemakers, magnetic stimulation, or electrical stimulation. Cranial repair has now become a relatively routine surgery in the medical field, the surgical risk is relatively small, but there are a few patients worrying or questioning about the impact of cranial repair on life expectancy, cranial repair surgery is not very difficult, will not move the intracranial soft tissues, no postoperative infection and other discomfort, after cranial repair, it is possible to resume normal life and does not affect life expectancy.