Atorvastatin calcium tablets and simvastatin are both common drugs used to lower blood lipids, the specific efficacy varies from person to person, the two can not be compared who is better. Atorvastatin Calcium Tablets can be used in conjunction with a low cholesterol diet for the treatment of hypercholesterolemia as well as coronary heart disease, or its critical combination of hypercholesterolemia or mixed dyslipidemia. Contraindications to the use of the drug include those with active liver disease, allergy to the drug, pregnant women, and lactating women. Common adverse drug reactions include nasopharyngitis, arthralgia, diarrhea, pain in the extremities, and urinary tract infections. Simvastatin tablets are also suitable for the treatment of hypercholesterolemia and coronary heart disease, should be contraindicated in people who are allergic to this product, active hepatitis or unexplained persistent elevation of serum aminotransferase, and prohibited from using in combination with mibefradil (belonging to the tetralin class of calcium channel blockers). Adverse reactions such as gastrointestinal distention, nausea, diarrhea, abdominal pain, constipation, fatigue, and weakness may occur after administration. The above two lipid-lowering drugs can not be clearly judged who is more effective, mainly because of the individual variability of drug users, making these two drugs have their own preference groups. The use of specific drugs should be guided by a specialist, not unauthorized use of drugs.