Some breast cancer patients, after surgery, especially after hearing the doctor say that it is radical surgery and the tumor has been removed, think that it is over and the cancer is far away from them and they can rest in peace from now on. In fact, it is not true. After the surgery to remove the tumor, there are still many things waiting for you to start doing. First of all, you have to understand the meaning of “complete remission, cure and post-radical surgery” in medical terminology, which means that the tumor lesion is undetectable by the current detection methods after treatment. However, undetectable tumor lesion does not mean that the number of tumor cells in human body is 0, and it does not mean that the cancer will not recur or metastasize. When a tumor lesion of 1mm3 size is already formed by millions of tumor cells, it is still too small to be detected by existing imaging methods, whether it is CT, MRI or PET-CT. Tumor cells divide from 1 cell to 2 cells, proliferate from 2 cells to 4 cells, and expand from 4 cells to 8 cells …… to grow into a 1cm tumor lesion, many things have happened in the process. Some tumor cells may have already metastasized to distant places, or grow into metastatic foci quickly, or not grow up temporarily, but wait for the right time to grow up again, like grains of seeds sown to distant places. This waiting process can be a few months, a few years, or a decade. Therefore, cancer patients need to be followed up regularly after surgery in order to detect recurrence and metastasis as early as possible, and this should be done throughout their life. Some patients also need adjuvant treatment after surgery to eliminate residual tumor lesions and consolidate the effect achieved by surgery in order to reduce the chance of recurrence, delay the time of recurrence and prolong survival. Post-operative adjuvant therapy includes: chemotherapy, radiotherapy, molecular targeted therapy, endocrine therapy. After surgery, patients need to submit the relevant information to the oncologist to develop an overall post-operative treatment and follow-up plan. The information to be provided to the oncologist includes: 1) disease stage, surgical specimens such as tumor location, size, number, tumor grade, pathological characteristics and proliferation of tumor cells, expression of Ki67, Her2, ER, PR, etc., distance between tumor and surgical margin. Lymph node biopsy. These postoperative pathological examinations will be described in detail.2. Imaging results related to tumor screening, such as ultrasound or MRI results of breast, imaging results of chest, abdomen and pelvis, bone scan results.3. General health condition of the patient, such as history of previous diseases, physical examination results, blood count, liver and kidney function, heart function, etc. The oncologist will decide whether the patient needs postoperative adjuvant therapy and what postoperative adjuvant therapy is needed based on clinical treatment guidelines and norms, new advances in clinical research, and the patient’s specific situation to develop an appropriate individualized overall strategy for postoperative treatment. Although postoperative adjuvant therapy includes chemotherapy, radiotherapy, molecular targeted therapy and endocrine therapy, not all patients need postoperative adjuvant therapy, some patients do not need any postoperative adjuvant therapy; even patients who need postoperative adjuvant therapy do not need all the adjuvant therapy, some patients need only one of these treatments, some patients need two of these treatments, some patients need Some patients need only one of these treatments, some patients need two of these treatments, some patients need three of these treatments, and some patients need all four of these treatments, which requires very specialized knowledge. In addition, the patient’s personal wishes, family and social situation are also taken into account when the doctor formulates the treatment strategy, including the patient’s desire to have another child. After surgery, the patient needs genetic counseling, that is, to determine if the cancer is hereditary. About one in ten patients have hereditary breast cancer. Tell your doctor your age, medical history, and family history, and he or she will help you assess how likely hereditary breast cancer is. Most hereditary breast cancers are caused by BRCA1,2 mutations and genetic testing is needed to find out if there is a mutation if necessary. Regarding breast reconstruction, it can be done at the same time as the mastectomy or at any time after the surgery. Once these are completed the patient is ready for adjuvant therapy as planned. Hoseltine is only indicated for patients with Her2 immunohistochemistry test 3+ and/or FISH test +, and is usually administered for one year; endocrine therapy is indicated for patients with ER, PR positive, including medications and oophorectomy with ovarian function suppression, and is mostly administered for more than 5 years. Regular postoperative follow-up is very important to understand the health status of patients, to detect tumor recurrence and metastasis as early as possible, and to understand the efficacy of treatment and the side effects of treatment. The follow-up includes medical history consultation and physical examination, which should be done every 4-6 months for 5 years and annually after 5 years. The healthy breast, lung, liver, bone, brain, lymph nodes and certain soft tissues are common sites of breast cancer recurrence and metastasis, and the oncologist will recommend the frequency of imaging screening for these sites based on the patient’s risk of recurrence and metastasis. It is important for patients undergoing endocrine therapy to adhere to their medication, which can effectively inhibit the growth of tumor cells. Adverse reactions should be promptly told to the doctor, and medication should be discontinued or changed only under the doctor’s supervision. Tamoxifen may increase the risk of uterine cancer. Regular gynecological examinations should be performed during this drug and any abnormal vaginal bleeding should be reported to the doctor in time. Patients with postmenopausal status or taking aromatase inhibitors have increased bone mineral loss, leading to osteoporosis, and need regular bone density checks and pharmacological intervention if necessary. In addition, healthy lifestyle habits are very important. It is important to exercise more and maintain an appropriate weight. Body mass index (BMI) can be used to measure whether the weight is appropriate, and it is good to keep the BMI between 20-25. BMI is calculated based on height and weight, and the formula is: BMI = weight (Kg) / height (m) squared.