Prostatectomy is a minimally invasive surgery, which usually does not directly lead to limb weakness, but to exclude the causes of anemia, ionic disorders, poor nutrition, low immunity and so on. Although prostatectomy is a minimally invasive surgery, if the prostate gland is relatively large, it may bleed more during the operation, which may cause the patient to be anemic, thus resulting in weakness of the limbs. After the operation, due to less diet and poor nutrition may cause ionic disorder, especially potassium ion and sodium ion deficiency, which may lead to weakness of limbs. After surgery, the body’s immunity is low, poor rest is also very easy to appear body fatigue and weakness. Therefore, if you have weakness after prostate surgery, you need to complete the relevant examinations to identify the specific cause of the disease and then give appropriate treatment.