Redness of skin all over the body after allogeneic transplantation may be due to rejection reaction. Rejection reaction may occur after allogeneic transplantation. Skin rejection may manifest as itching, redness, rash, etc., which occurs on the palms of the hands, soles of the feet, etc., and can also be seen on the whole body in severe cases, and can be treated with prednisolone and cyclosporine. Allogeneic transplantation has a high risk of rejection reaction, which can lead to adverse reactions such as jaundice, hepatomegaly, ascites, diarrhea, abdominal pain, etc., in addition to skin reactions, and poor dietary habits can trigger the occurrence of digestive tract rejection reaction. After allogeneic transplantation, it will lead to a short-term decrease in immunity, and attention needs to be paid to prevent the occurrence of infections, as well as monitoring liver function to avoid serious liver damage. Specific diagnosis and treatment need to be carried out under the guidance of physicians.