Bone tuberculosis after ten months of medication is still not good need to continue anti-tuberculosis drug treatment, and regular review, serious cases of lesion removal bone grafting treatment. The treatment of bone tuberculosis is mainly standardized anti-tuberculosis drug treatment, drug treatment principle is early, regular, whole, combined, appropriate amount, commonly used drugs are isoniazid, rifampicin, pyrazinamide, streptomycin, ethambutol and so on. The treatment cycle of bone tuberculosis is generally 12~24 months, so ten months of drug treatment can not completely control bone tuberculosis. During the treatment of bone tuberculosis, on the one hand, there will be some adverse reactions to drug treatment, such as abnormal liver function and kidney function. On the other hand, regular review can understand the recovery of bone tuberculosis and the effect of treatment. For severe bone tuberculosis, if there is dead bone and sinus tract formation, regular anti-tuberculosis treatment for 4 weeks can be carried out, followed by lesion debridement, or combined with bone grafting and implantation and other treatment measures, which will in turn improve the function.